Fas-mediated apoptosis and expression of related genes in human malignant hematopoietic cells
نویسندگان
چکیده
منابع مشابه
Fas-mediated apoptosis and expression of related genes in human malignant hematopoietic cells.
Fas transduces apoptotic signals upon cross-linking with the Fas ligand (FasL), which is experimentally replaced by agonistic anti-Fas monoclonal antibodies (mAb). Of eight human malignant hematopoietic cell lines (HL-60, KG-1, THP-1, K562, U937, Jurkat, IM-9, RPMI-8226) examined by flow cytometric analysis, all, except K562, were found to be positive for surface Fas antigen. However, despite s...
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ژورنال
عنوان ژورنال: Experimental & Molecular Medicine
سال: 2000
ISSN: 2092-6413
DOI: 10.1038/emm.2000.41